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What is the main use of hydroxychloroquine?

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  • What is the main use of hydroxychloroquine?

    It is primarily used to treat and prevent malaria, a mosquito-borne infectious disease caused by Plasmodium parasites. Additionally, it is prescribed to manage certain autoimmune conditions such as rheumatoid arthritis and lupus erythematosus due to its anti-inflammatory properties. However, it's important to note that hydroxychloroquine should only be used under the supervision of a healthcare professional and for approved indications, as misuse or overuse can lead to serious side effects.




    Treatment of Rheumatoid Arthritis: Hydroxychloroquine is commonly prescribed as a disease-modifying antirheumatic drug (DMARD) for the treatment of rheumatoid arthritis. It helps reduce joint pain, swelling, and inflammation associated with this autoimmune condition.


    Management of Systemic Lupus Erythematosus (SLE): Hydroxychloroquine is also used in the management of systemic lupus erythematosus (SLE), another autoimmune disorder. It can help control symptoms such as joint pain, skin rashes, and fatigue, and may also reduce the risk of disease flares.


    Off-Label Uses: In addition to its approved indications, hydroxychloroquine has been investigated for various off-label uses, including the treatment of certain viral infections such as HIV and COVID-19. However, evidence supporting its efficacy for these purposes is limited and controversial, and its use for off-label indications should be approached with caution.


    Synergistic Effects: Hydroxychloroquine is sometimes used in combination with other medications, such as methotrexate or corticosteroids, to enhance its therapeutic effects in rheumatoid arthritis and lupus. This combination therapy may allow for lower doses of each medication, reducing the risk of side effects while maintaining efficacy.


    Long-Term Use: Hydroxychloroquine is often prescribed for long-term use in patients with rheumatoid arthritis or lupus to help manage chronic symptoms and prevent disease progression. Regular monitoring of patients, including eye examinations to detect potential retinal toxicity, is essential for safe long-term use.
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